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产品目录

DFF45/DFFA抗体图片
产品货号:
Z31290
中文名称:
DFF45/DFFA抗体
英文名称:
Anti-DFF45/DFFA Antibody (Clone#OTI5C4)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-DFF45/DFFA Antibody (Clone#OTI5C4)
指标别名DFF 45;DFF1;DFF45;DFF45/DFFA;DFFA;ICAD;Inhibitor of CAD
克隆性Monoclonal
检验物种human
应用范围WB,IF
基因名称DFFA
克隆号OTI5C4
抗体来源Mouse
抗体类型IgG1
免疫原Full length human recombinant protein of human DFFA (NP_004392) produced in E.coli.
实际分子量36.3KD
成分PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide.
纯化方式Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
浓度0.2mg/mL
产品形态溶液
保存条件Stable for 12 months from date of receipt.Store at -20℃ as received.
背景资料Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development.The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units.DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits.DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis.DFF becomes activated when DFFA is cleaved by caspase-3.The cleaved fragments of DFFA dissociate from DFFB,the active component of DFF.DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis.Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Uniprot IDO00273
基因名全称DNA fragmentation factor subunit alpha|DNA fragmentation factor 45kDa subunit|DFF-45|Inhibitor of CAD|ICAD
推荐稀释比
Western blot (WB) 1:2500~5000
Immunofluorescence (IF) 1:50~100

相关搜索:DFF45/DFFA抗体DFF45抗体DFFA单抗Anti-DFF45/DFFA Antibody (Clone#OTI5C4)
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